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Table 4 Accuracy prediction of PCR-SBT, HLAreporter, and HLAscan using samples from five Korean subjects

From: HLAscan: genotyping of the HLA region using next-generation sequencing data

Samples

Method

HLA-A

HLA-B

HLA-DRB1

77072421 NS1512240004

PCR-SBT

02:06

02:10

40:02

55:02

04:05

11:01

HLAreporter

02:10

02:10

40:02:01

55:02:01

04:05:01

11:01:01

HLAscan

02:06:01

02:10

40:02:01

55:02:01

04:05:01

11:01:01

77072412 NS1512240008

PCR-SBT

24:02

31:01

35:01

51:02

09:01

09:01

HLAreporter

24:82

31:01:02

35:42:02

51:02:02

09:01:02

09:01:02

HLAscan

24:02:01

31:01:13

35:01:01

51:02:01

09:01:02

09:01:02

77072374 NS1512240012

PCR-SBT

02:01

33:03

15:01

44:03

09:01

13:02

HLAreporter

02:01:01

33:03:01

15:01:01

44:03:11

09:01:02

13:02:01

HLAscan

02:01:01

33:03:23

15:01:01

44:03:01

09:01:02

13:02:01

77072406 NS1512240016

PCR-SBT

11:01

26:01

44:02

46:01

09:01

13:01

HLAreporter

11:01:01

26:01:01

44:02:01

46:01:01

09:01:02

13:01:01

HLAscan

11:01:01:01

26:01:01:01

44:02:01

46:01:01

09:01:02

13:01:01

77072287 NS1512240020

PCR-SBT

02:01

02:06

13:01

40:02

08:02

12:02

HLAreporter

02:01:01

02:01:01

13:01:01

40:02:01

08:02:01

12:02:01

HLAscan

02:01:01

02:06:01

13:01:01

40:02:01

08:02:01

12:02:01

  1. Typing results different from those obtained by SBT methods are marked in red