Skip to main content
Fig. 2 | BMC Bioinformatics

Fig. 2

From: Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Fig. 2

Analysis of success and failure rates in protein docking. Spectrum plots are constructed for (a, b) crystal monomer structures and (c, d) protein models. Successful docking cases shown in green correspond to those predictions for which at least one native-like configuration with an IS-score greater than a value display on the x-axis is ranked within the top 10 poses by (a, c) ZDOCK and (b, d) eRankPPI. The remaining cases represent two types of docking failures. Scoring failures shown in red correspond to those predictions in which at least one native-like configuration is present in a set of 2,000 dimer models, however, it was not ranked within the top 10 poses. Sampling failures shown in yellow correspond to the remaining cases for which no native-like configurations have been generated

Back to article page