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Table 2 Accuracy of the prediction of biologically relevant PPIs for the HET3519 and RND14944 datasets

From: Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Number of models

MCC

TPR

FPR

1

0.43

0.53

0.11

2

0.58

0.74

0.14

3

0.61

0.81

0.19

4

0.58

0.85

0.20

5

0.58

0.88

0.22

  1. Here, we consider up to top 5 ranked models constructed for a given pair of receptor and ligand proteins
  2. MCC Matthews correlation coefficient, TPR true positive rate, FPR false positive rate