Fig. 3
From: AGeNNT: annotation of enzyme families by means of refined neighborhood networks
rGNN of IPR023016 (HisA/PriA). PriA is a bifunctional enzyme that adopts the roles of both HisA in histidine and of TrpF in tryptophan biosynthesis. Cluster-node 1 contains the actinobacterial HisA homologs (PriA) and cluster-nodes 4 and 42 homologs from different Bacteria. The GNs of all three cluster-nodes overlap to a great extent and consist of enzymes involved in histidine biosynthesis. The Pfams belonging to the overlap of GNs are arranged in a line