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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data

Fig. 1

Workflow of Hapl-o-Mat. The main process is divided into data preprocessing and estimation of haplotype frequencies via the EM algorithm. The data preparation is illustrated for one individual MLG, which is split into several SLGs. After all individuals are processed, the estimation of haplotype frequencies starts. Expectation and maximization steps alternate until the stop criterion is fulfilled

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BMC Bioinformatics

ISSN: 1471-2105

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