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Table 1 Definitions of HLA typing resolutions and allele groups. For example, HLA alleles whose names share the same first two fields code for identical amino acid sequence. Hapl-o-Mat is able to translate between these typing resolutions and groups

From: Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data

Resolution/group

Definition

1 field

HLA alleles of identical allele group

2 fields

HLA alleles with identical amino acid sequences

3 fieldsa

HLA alleles with identical nucleotide sequences within the coding region

4 fieldsa

HLA alleles with identical nucleotide sequences within coding and non-coding (introns or 5' or 3' untranslated) regions

G

HLA class I (II) alleles with identical nucleotide sequences across exons 2 and 3 (2)

P

HLA class I (II) expressed alleles with identical amino acid sequences across exons 2 and 3 (2)

g

HLA class I (II) expressed and null alleles with identical amino acid sequences across exons 2 and 3 (2)

  1. aWithin the HLA nomenclature, 2 field designations comprise more field designations if the 2 field designation actually groups more than one allele, only. If the 2 field designation is already the full length designation, it is used as equivalent to 3 and 4 field designations in this paper