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Table 2 Influence of explanatory variables on pathogen/non-pathogen classification when considering genomic, physiological, and network parameters in addition to reverse ecology-based measures

From: Limitations of a metabolic network-based reverse ecology method for inferring host–pathogen interactions

Variables

Mammalian pathogens

Plant pathogens

Insect pathogens

Estimate[Averaged]

Estimate[Best]

Estimate[Averaged]

Estimate[Best]

Estimate[Averaged]

Estimate[Best]

BSSHM

0.841 (0.29)

 

2.17 (0.08)

2.347 (0.01)

0.133 (0.90)

 

BSSMH

−0.838 (0.35)

 

0.674 (0.60)

 

−1.042 (0.41)

1.129 (0.06)

MCIHM

−0.143 (0.86)

 

−1.758 (0.19)

−2.124 (0.05)

0.534 (0.53)

 

MCIMH

−0.696 (0.07)

−0.752 (0.03)

1.819 (0.01)

2.134 (<0.01)

1.207 (0.10)

 

Genome size

−1.951 (0.16)

−2.621 (0.04)

0.657 (0.73)

 

−1.326 (0.47)

 

#Genes

1.631 (0.29)

1.812 (0.15)

−1.193 (0.54)

 

0.561 (0.80)

 

Oxygen

−1.726 (<0.01)

−1.646 (0.01)

−16.211 (0.99)

 

−18.171 (0.99)

−18.264 (0.99)

N

−4.564 (<0.01)

−4.874 (<0.01)

−0.615 (0.78)

 

−7.541 (<0.01)

−8.816 (<0.01)

E

5.552 (<0.01)

5.79 (<0.01)

1.64 (0.33)

 

7.181 (<0.01)

7.213 (<0.01)

Q

−0.307 (0.17)

 

0.367 (0.33)

 

−0.656 (0.09)

−0.577 (0.10)

AICc

 

241.7

 

87.6

 

90.3

  1. The variable “Oxygen” indicates the species oxygen requirement (i.e., anaerobe or not). N and E correspond to the number of nodes and number of directed edges, respectively. Q indicates network modularity. See the footnote to Table 1 for a description of all other table elements