TY - STD TI - N. M. Antikainen and S. F. Martin, “Altering protein specificity: techniques and applications” ID - ref1 ER - TY - JOUR AU - Lefèvre, F. AU - Rémy, M. H. AU - Masson, J. M. PY - 1997 DA - 1997// TI - Alanine-stretch scanning mutagenesis: a simple and efficient method to probe protein structure and function JO - Nucleic Acids res VL - 25 UR - https://doi.org/10.1093/nar/25.2.447 DO - 10.1093/nar/25.2.447 ID - Lefèvre1997 ER - TY - JOUR AU - Thorn, K. S. AU - Bogan, A. A. PY - 2001 DA - 2001// TI - ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions JO - Bioinformatics VL - 17 UR - https://doi.org/10.1093/bioinformatics/17.3.284 DO - 10.1093/bioinformatics/17.3.284 ID - Thorn2001 ER - TY - BOOK AU - Brachman, R. J. AU - Levesque, H. J. PY - 1985 DA - 1985// TI - Readings in knowledge representation PB - M. Kaufmann Publishers CY - Burlington, MA ID - Brachman1985 ER - TY - JOUR AU - Bengio, Y. AU - Courville, A. AU - Vincent, P. PY - 2013 DA - 2013// TI - Representation learning: a review and new perspectives JO - Pattern Anal Mach Intell IEEE Trans VL - 35 UR - https://doi.org/10.1109/TPAMI.2013.50 DO - 10.1109/TPAMI.2013.50 ID - Bengio2013 ER - TY - JOUR AU - Bagley, S. C. AU - Altman, R. B. PY - 1995 DA - 1995// TI - Characterizing the microenvironment surrounding protein sites JO - Protein Sci VL - 4 UR - https://doi.org/10.1002/pro.5560040404 DO - 10.1002/pro.5560040404 ID - Bagley1995 ER - TY - JOUR AU - Neshich, G. PY - 2005 DA - 2005// TI - STING report: convenient web-based application for graphic and tabular presentations of protein sequence, structure and function descriptors from the STING database JO - Nucleic Acids res VL - 33 ID - Neshich2005 ER - TY - JOUR AU - Block, P. AU - Paern, J. AU - Hüllermeier, E. AU - Sanschagrin, P. AU - Sotriffer, C. A. AU - Klebe, G. PY - 2006 DA - 2006// TI - Physicochemical descriptors to discriminate protein-protein interactions in permanent and transient complexes selected by means of machine learning algorithms JO - Proteins Struct Funct Genet VL - 65 UR - https://doi.org/10.1002/prot.21104 DO - 10.1002/prot.21104 ID - Block2006 ER - TY - JOUR AU - Zvelebil, M. J. J. M. AU - Sternberg, M. J. E. PY - 1988 DA - 1988// TI - Analysis and prediction of the location of catalytic residues in enzymes JO - Protein Eng Des Sel VL - 2 UR - https://doi.org/10.1093/protein/2.2.127 DO - 10.1093/protein/2.2.127 ID - Zvelebil1988 ER - TY - JOUR AU - Buturovic, L. AU - Wong, M. AU - Tang, G. W. AU - Altman, R. B. AU - Petkovic, D. PY - 2014 DA - 2014// TI - High precision prediction of functional sites in protein structures JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0091240 DO - 10.1371/journal.pone.0091240 ID - Buturovic2014 ER - TY - JOUR AU - Liu, T. AU - Altman, R. B. PY - 2011 DA - 2011// TI - Using multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor binding JO - PLoS Comput Biol VL - 7 UR - https://doi.org/10.1371/journal.pcbi.1002326 DO - 10.1371/journal.pcbi.1002326 ID - Liu2011 ER - TY - JOUR AU - Tang, G. W. AU - Altman, R. B. PY - 2014 DA - 2014// TI - Knowledge-based fragment binding prediction JO - PLoS Comput Biol VL - 10 UR - https://doi.org/10.1371/journal.pcbi.1003589 DO - 10.1371/journal.pcbi.1003589 ID - Tang2014 ER - TY - STD TI - Liang MP, Brutlag DL and Altman RB. “Automated construction of structural motifs for predicting functional sites on protein structures.” Pac Symp Biocomput. 2003; pp. 204–15 ID - ref13 ER - TY - BOOK AU - Bishop, C. M. PY - 2006 DA - 2006// TI - Pattern recognition ID - Bishop2006 ER - TY - JOUR AU - Grabowski, M. AU - Chruszcz, M. AU - Zimmerman, M. D. AU - Kirillova, O. AU - Minor, W. PY - 2009 DA - 2009// TI - Benefits of structural genomics for drug discovery research JO - Infect Disord Drug Targets VL - 9 UR - https://doi.org/10.2174/187152609789105704 DO - 10.2174/187152609789105704 ID - Grabowski2009 ER - TY - JOUR AU - LeCun, Y. AU - Bengio, Y. AU - Hinton, G. PY - 2015 DA - 2015// TI - Deep learning JO - Nature VL - 521 UR - https://doi.org/10.1038/nature14539 DO - 10.1038/nature14539 ID - LeCun2015 ER - TY - STD TI - Krizhevsky A, Sutskever I and Hinton GE. “ImageNet classification with deep convolutional neural networks.” Adv Neural Inf Process Syst. 2012; pp. 1–9 ID - ref17 ER - TY - STD TI - Szegedy C. et al., “Going deeper with convolutions,” in Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition, 2015, vol. 07–12–June, pp. 1–9 ID - ref18 ER - TY - STD TI - Bahdana D, Bahdanau D, Cho K and Bengio Y. “Neural Machine Translation By Jointly Learning To Align and Translate.” Int Conf Learn Represent. 2015, no. http://arxiv.org/abs/1409.0473, pp. 1–15, 2015 Submitted on 1 Sep 2014 (v1), last revised 19 May 2016 (this version, v7)) UR - http://arxiv.org/abs/1409.0473 ID - ref19 ER - TY - JOUR AU - Kearnes, S. AU - McCloskey, K. AU - Berndl, M. AU - Pande, V. AU - Riley, P. PY - 2016 DA - 2016// TI - Molecular graph convolutions: moving beyond fingerprints JO - J Comput Aided Mol des VL - 30 UR - https://doi.org/10.1007/s10822-016-9938-8 DO - 10.1007/s10822-016-9938-8 ID - Kearnes2016 ER - TY - JOUR AU - Duvenaud, D. PY - 2015 DA - 2015// TI - Convolutional networks on graphs for learning molecular fingerprints JO - Adv Neural Inf Process Syst VL - 28 ID - Duvenaud2015 ER - TY - JOUR AU - Alipanahi, B. AU - Delong, A. AU - Weirauch, M. T. AU - Frey, B. J. PY - 2015 DA - 2015// TI - Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning JO - Nat Biotechnol VL - 33 UR - https://doi.org/10.1038/nbt.3300 DO - 10.1038/nbt.3300 ID - Alipanahi2015 ER - TY - JOUR AU - Zhou, J. AU - Troyanskaya, O. G. PY - 2015 DA - 2015// TI - Predicting effects of noncoding variants with deep learning-based sequence model JO - Nat Methods VL - 12 UR - https://doi.org/10.1038/nmeth.3547 DO - 10.1038/nmeth.3547 ID - Zhou2015 ER - TY - STD TI - R. Miotto, L. Li, B. A. Kidd, and J. T. Dudley, “Deep patient: an unsupervised representation to predict the future of patients from the electronic health records.,” Sci rep., vol. 6, no. April, p. 26094, 2016. ID - ref24 ER - TY - BOOK AU - Cun, Y. PY - 1989 DA - 1989// TI - “Handwritten digit recognition with a back-propagation network.” Proceedings of the 2nd International Conference on Neural Information Processing Systems PB - MIT Press CY - Cambridge, MA ID - Cun1989 ER - TY - STD TI - Wallach I, Dzamba M, and Heifets A. “AtomNet: A Deep Convolutional Neural Network for Bioactivity Prediction in Structure-based Drug Discover.” arXiv Prepr. arXiv1510.02855. 2015 pp. 1–11 ID - ref26 ER - TY - JOUR AU - Henikoff, S. AU - Henikoff, J. G. PY - 1992 DA - 1992// TI - Amino acid substitution matrices from protein blocks JO - Proceedings of the National Academy of Sciences VL - 89 UR - https://doi.org/10.1073/pnas.89.22.10915 DO - 10.1073/pnas.89.22.10915 ID - Henikoff1992 ER - TY - STD TI - B. C. Dayhoff, M.O., Schwartz, R. and Orcutt, “A Model of Evolutionary Change in Proteins,” in Atlas of protein sequence and structure, Volume 5,., National Biomedical Research Foundation Silver Spring, MD, 1978, pp. 345–358 ID - ref28 ER - TY - STD TI - Wei L, AltmanRB, and Chang JT. “Using the radial distributions of physical features to compare amino acid environments and align amino acid sequences.” Pac Symp Biocomput. 1997; pp. 465–76 ID - ref29 ER - TY - JOUR AU - Murzin, A. G. AU - Brenner, S. E. AU - Hubbard, T. AU - Chothia, C. PY - 1995 DA - 1995// TI - SCOP: a structural classification of proteins database for the investigation of sequences and structures JO - J Mol Biol VL - 247 ID - Murzin1995 ER - TY - JOUR AU - Brenner, S. E. AU - Koehl, P. AU - Levitt, M. PY - 2000 DA - 2000// TI - The ASTRAL compendium for protein structure and sequence analysis JO - Nucleic Acids res VL - 28 UR - https://doi.org/10.1093/nar/28.1.254 DO - 10.1093/nar/28.1.254 ID - Brenner2000 ER - TY - JOUR AU - Huang, Y. AU - Niu, B. AU - Gao, Y. AU - Fu, L. AU - Li, W. PY - 2010 DA - 2010// TI - CD-HIT suite: a web server for clustering and comparing biological sequences JO - Bioinformatics VL - 26 UR - https://doi.org/10.1093/bioinformatics/btq003 DO - 10.1093/bioinformatics/btq003 ID - Huang2010 ER - TY - JOUR AU - Bateman, A. PY - 2015 DA - 2015// TI - UniProt: a hub for protein information JO - Nucleic Acids res VL - 43 UR - https://doi.org/10.1093/nar/gku989 DO - 10.1093/nar/gku989 ID - Bateman2015 ER - TY - STD TI - Scherer D, Müller A, and Behnke S. “Evaluation of pooling operations in convolutional architectures for object recognition.” International Conference on Artificial Neural Networks. Springer Berlin Heidelberg. 2010; LNCS, vol. 6354: pp 92-101 ID - ref34 ER - TY - CHAP AU - Bridle, J. S. PY - 1990 DA - 1990// TI - Probabilistic interpretation of feedforward classification network outputs, with relationships to statistical pattern recognition BT - Neurocomputing PB - Springer Berlin Heidelberg CY - Berlin UR - https://doi.org/10.1007/978-3-642-76153-9_28 DO - 10.1007/978-3-642-76153-9_28 ID - Bridle1990 ER - TY - STD TI - Theano Development Team. “Theano: A Python framework for fast computation of mathematical expressions.” arXiv e-prints arXiv.abs/1605.02688. 2016; p. 19 ID - ref36 ER - TY - JOUR AU - Glorot, X. AU - Bordes, A. AU - Bengio, Y. PY - 2011 DA - 2011// TI - Deep sparse rectifier neural networks JO - AISTATS ‘11 Proc 14th Int Conf Artif Intell Stat VL - 15 ID - Glorot2011 ER - TY - STD TI - Bottou L. “Large-Scale Machine Learning with Stochastic Gradient Descent.” Proc. COMPSTAT’2010. 2010; pp. 177–186 ID - ref38 ER - TY - JOUR AU - Rumelhart, D. E. AU - Hinton, G. E. AU - Williams, R. J. PY - 1986 DA - 1986// TI - Learning representations by back-propagating errors JO - Nature VL - 323 UR - https://doi.org/10.1038/323533a0 DO - 10.1038/323533a0 ID - Rumelhart1986 ER - TY - JOUR AU - Srivastava, N. AU - Hinton, G. AU - Krizhevsky, A. AU - Sutskever, I. AU - Salakhutdinov, R. PY - 2014 DA - 2014// TI - Dropout: a simple way to prevent neural networks from Overfitting JO - J Mach Learn res VL - 15 ID - Srivastava2014 ER - TY - STD TI - Gu J and Bourne PE. Structural bioinformatics. Wiley-Blackwell, Hoboken, New Jersey; 2009. ID - ref41 ER - TY - STD TI - J. H. Ward, “Hierarchical grouping to optimize an objective function,” J am Stat Assoc, vol. 58, no. 301. pp. 236–244, Mar-1963. ID - ref42 ER - TY - JOUR AU - Oliphant, T. E. PY - 2007 DA - 2007// TI - Python for scientific computing JO - Comput Sci Eng VL - 9 UR - https://doi.org/10.1109/MCSE.2007.58 DO - 10.1109/MCSE.2007.58 ID - Oliphant2007 ER - TY - JOUR AU - Chandonia, J. -. M. AU - Fox, N. K. AU - Brenner, S. E. PY - 2016 DA - 2016// TI - SCOPe: Manual Curation and Artifact Removal in the Structural Classification of Proteins – extended Database JO - J. Mol. Biol VL - 429 UR - https://doi.org/10.1016/j.jmb.2016.11.023 DO - 10.1016/j.jmb.2016.11.023 ID - Chandonia2016 ER - TY - JOUR AU - Weaver, L. H. AU - Matthews, B. W. PY - 1987 DA - 1987// TI - Structure of bacteriophage T4 lysozyme refined at 1.7 Å Resolution JO - J Mol Biol VL - 193 UR - https://doi.org/10.1016/0022-2836(87)90636-X DO - 10.1016/0022-2836(87)90636-X ID - Weaver1987 ER - TY - JOUR AU - Tibshirani, R. PY - 1996 DA - 1996// TI - Regression selection and shrinkage via the Lasso JO - J R Stat Soc B VL - 58 ID - Tibshirani1996 ER - TY - JOUR AU - Cortes, C. AU - Vapnik, V. PY - 1995 DA - 1995// TI - Support vector networks JO - Mach Learn VL - 20 ID - Cortes1995 ER - TY - STD TI - Simonyan K, Vedaldi A, and Zisserman A. “Deep Inside Convolutional Networks: Visualising Image Classification Models and Saliency Maps.” Proc Int Conf Learn Represent. 2014 ID - ref48 ER - TY - STD TI - “The PyMOL Molecular Graphics System, Version 1.8 Schrödinger, LLC” ID - ref49 ER - TY - JOUR AU - Janiak, C. PY - 2000 DA - 2000// TI - A critical account on π–π stacking in metal complexes with aromatic nitrogen-containing ligands † JO - Dalton Trans VL - 21 UR - https://doi.org/10.1039/b003010o DO - 10.1039/b003010o ID - Janiak2000 ER - TY - JOUR AU - Alvarez, S. PY - 2013 DA - 2013// TI - A cartography of the van der Waals territories JO - Dalt Trans VL - 42 UR - https://doi.org/10.1039/c3dt50599e DO - 10.1039/c3dt50599e ID - Alvarez2013 ER - TY - STD TI - Betts MJ, Russell RB. Amino acid properties and consequences of substitutions. In: Bioinformatics for geneticists. Chichester: John Wiley & Sons, Ltd. p. 289–316. ID - ref52 ER - TY - STD TI - W. A. Baase, L. Liu, D. E. Tronrud, and B. W. Matthews, “Lessons from the lysozyme of phage T4,” Protein Sci, vol. 19, no. 4. Wiley-Blackwell, pp. 631–641, Apr-2010. ID - ref53 ER - TY - JOUR AU - Rennell, D. AU - Bouvier, S. E. AU - Hardy, L. W. AU - Poteete, A. R. PY - 1991 DA - 1991// TI - Systematic mutation of bacteriophage T4 lysozyme JO - J Mol Biol VL - 222 UR - https://doi.org/10.1016/0022-2836(91)90738-R DO - 10.1016/0022-2836(91)90738-R ID - Rennell1991 ER - TY - JOUR AU - Kawasaki, H. AU - Kretsinger, R. H. PY - 1995 DA - 1995// TI - Calcium-binding proteins 1: EF-hands JO - Protein Profile VL - 2 ID - Kawasaki1995 ER - TY - JOUR AU - Moncrief, N. D. AU - Kretsinger, R. H. AU - Goodman, M. PY - 1990 DA - 1990// TI - Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences JO - J Mol Evol VL - 30 UR - https://doi.org/10.1007/BF02101108 DO - 10.1007/BF02101108 ID - Moncrief1990 ER - TY - JOUR AU - Vassylyev, D. G. AU - Takeda, S. AU - Wakatsuki, S. AU - Maeda, K. AU - Maéda, Y. PY - 1998 DA - 1998// TI - Crystal structure of troponin C in complex with troponin I fragment at 2.3-a resolution JO - Proc Natl Acad Sci U S a VL - 95 UR - https://doi.org/10.1073/pnas.95.9.4847 DO - 10.1073/pnas.95.9.4847 ID - Vassylyev1998 ER - TY - JOUR AU - Sigrist, C. J. A. PY - 2010 DA - 2010// TI - PROSITE, a protein domain database for functional characterization and annotation JO - Nucleic Acids res VL - 38 UR - https://doi.org/10.1093/nar/gkp885 DO - 10.1093/nar/gkp885 ID - Sigrist2010 ER - TY - JOUR AU - Blundell, T. L. AU - Humbel, R. E. PY - 1980 DA - 1980// TI - Hormone families: pancreatic hormones and homologous growth factors JO - Nature VL - 287 UR - https://doi.org/10.1038/287781a0 DO - 10.1038/287781a0 ID - Blundell1980 ER - TY - JOUR AU - Bentley, G. A. PY - 1992 DA - 1992// TI - Role of B13 Glu in insulin assembly: the hexamer structure of recombinant mutant (B13 Glu → Gln) insulin JO - J Mol Biol VL - 228 UR - https://doi.org/10.1016/0022-2836(92)90323-C DO - 10.1016/0022-2836(92)90323-C ID - Bentley1992 ER - TY - JOUR AU - Buts, L. PY - 2005 DA - 2005// TI - Impact of natural variation in bacterial F17G adhesins on crystallization behaviour JO - Acta Crystallogr Sect D Biol Crystallogr VL - 61 UR - https://doi.org/10.1107/S0907444905017038 DO - 10.1107/S0907444905017038 ID - Buts2005 ER - TY - JOUR AU - Schweinitz, A. PY - 2004 DA - 2004// TI - Design of Novel and Selective Inhibitors of Urokinase-type Plasminogen activator with improved pharmacokinetic properties for use as Antimetastatic agents JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M314151200 DO - 10.1074/jbc.M314151200 ID - Schweinitz2004 ER - TY - STD TI - I. Halperin, D. S. Glazer, S. Wu, and R. B. Altman, “The FEATURE framework for protein function annotation: modeling new functions, improving performance, and extending to novel applications.,” BMC Genomics, vol. 9 Suppl 2, no. Suppl 2, p. S2, 2008. ID - ref63 ER - TY - STD TI - B. W. Matthews, H. Nicholson, and W. J. Becktel, “Enhanced protein Thermostability from site-directed mutations that decrease the entropy of unfolding.,” Proc Natl Acad Sci U S a., vol. 84, no. October, pp. 6663–6667, 1987. ID - ref64 ER - TY - JOUR AU - Pjura, P. AU - Matthews, B. W. PY - 1993 DA - 1993// TI - Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent JO - Protein Sci VL - 2 UR - https://doi.org/10.1002/pro.5560021222 DO - 10.1002/pro.5560021222 ID - Pjura1993 ER - TY - JOUR AU - Gassner, N. C. AU - Baase, W. A. AU - Lindstrom, J. D. AU - Lu, J. AU - Dahlquist, F. W. AU - Matthews, B. W. PY - 1999 DA - 1999// TI - Methionine and alanine substitutions show that the formation of wild- type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate- limiting step in folding JO - Biochemistry VL - 38 UR - https://doi.org/10.1021/bi9915519 DO - 10.1021/bi9915519 ID - Gassner1999 ER - TY - JOUR AU - Nicholson, H. AU - Anderson, D. E. AU - Dao Pin, S. AU - Matthews, B. W. PY - 1991 DA - 1991// TI - Analysis of the interaction between charged side chains and the .Alpha.-helix dipole using designed thermostable mutants of phage T4 lysozyme JO - Biochemistry VL - 30 UR - https://doi.org/10.1021/bi00105a002 DO - 10.1021/bi00105a002 ID - Nicholson1991 ER - TY - JOUR AU - Nicholson, H. AU - Becktel, W. J. AU - Matthews, B. W. PY - 1988 DA - 1988// TI - Enhanced protein thermostability from designed mutations that interact with α-helix dipoles JO - Nature VL - 336 UR - https://doi.org/10.1038/336651a0 DO - 10.1038/336651a0 ID - Nicholson1988 ER - TY - JOUR AU - Mooers, B. H. M. AU - Datta, D. AU - Baase, W. A. AU - Zollars, E. S. AU - Mayo, S. L. AU - Matthews, B. W. PY - 2003 DA - 2003// TI - Repacking the Core of T4 lysozyme by automated design JO - J Mol Biol VL - 332 UR - https://doi.org/10.1016/S0022-2836(03)00856-8 DO - 10.1016/S0022-2836(03)00856-8 ID - Mooers2003 ER - TY - JOUR AU - Xu, J. AU - Baase, W. A. AU - Quillin, M. L. AU - Baldwin, E. P. AU - Matthews, B. W. PY - 2001 DA - 2001// TI - Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme JO - Protein Sci VL - 10 UR - https://doi.org/10.1110/ps.02101 DO - 10.1110/ps.02101 ID - Xu2001 ER - TY - JOUR AU - Wray, J. W. AU - Baase, W. A. AU - Lindstrom, J. D. AU - Weaver, L. H. AU - Poteete, A. R. AU - Matthews, B. W. PY - 1999 DA - 1999// TI - Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability JO - J Mol Biol VL - 292 UR - https://doi.org/10.1006/jmbi.1999.3102 DO - 10.1006/jmbi.1999.3102 ID - Wray1999 ER - TY - JOUR AU - Anderson, D. E. AU - Hurley, J. H. AU - Nicholson, H. AU - Baase, W. A. AU - Matthews, B. W. PY - 1993 DA - 1993// TI - Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme ser 117 → phe JO - Protein Sci VL - 2 UR - https://doi.org/10.1002/pro.5560020811 DO - 10.1002/pro.5560020811 ID - Anderson1993 ER - TY - JOUR AU - Lipscomb, L. A. PY - 1998 DA - 1998// TI - Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme JO - Protein Sci VL - 7 UR - https://doi.org/10.1002/pro.5560070326 DO - 10.1002/pro.5560070326 ID - Lipscomb1998 ER - TY - JOUR AU - Matsumura, M. AU - Becktel, W. J. AU - Matthews, B. W. PY - 1988 DA - 1988// TI - Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3 JO - Nature VL - 334 UR - https://doi.org/10.1038/334406a0 DO - 10.1038/334406a0 ID - Matsumura1988 ER - TY - JOUR AU - Dao-Pin, S. AU - Anderson, D. E. AU - Baase, W. A. AU - Dahlquist, F. W. AU - Matthews, B. W. PY - 1991 DA - 1991// TI - Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme JO - Biochemistry VL - 30 UR - https://doi.org/10.1021/bi00113a006 DO - 10.1021/bi00113a006 ID - Dao-Pin1991 ER - TY - JOUR AU - Grütter, M. G. AU - Gray, T. M. AU - Weaver, L. H. AU - Alber, T. AU - Wilson, K. AU - Matthews, B. W. PY - 1987 DA - 1987// TI - Structural studies of mutants of the lysozyme of bacteriophage T4: the temperature-sensitive mutant protein Thr157 → Ile JO - J Mol Biol VL - 197 UR - https://doi.org/10.1016/0022-2836(87)90126-4 DO - 10.1016/0022-2836(87)90126-4 ID - Grütter1987 ER - TY - JOUR AU - Gray, T. M. AU - Matthews, B. W. PY - 1987 DA - 1987// TI - Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid JO - J Biol Chem VL - 262 ID - Gray1987 ER - TY - JOUR AU - Weaver, L. H. PY - 1989 DA - 1989// TI - High-resolution structure of the temperature-sensitive mutant of phage lysozyme, Arg 96 .Fwdarw. His JO - Biochemistry VL - 28 UR - https://doi.org/10.1021/bi00435a025 DO - 10.1021/bi00435a025 ID - Weaver1989 ER - TY - JOUR AU - Dixon, M. M. AU - Nicholson, H. AU - Shewchuk, L. AU - Baase, W. A. AU - Matthews, B. W. PY - 1992 DA - 1992// TI - Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3 → pro JO - J Mol Biol VL - 227 UR - https://doi.org/10.1016/0022-2836(92)90231-8 DO - 10.1016/0022-2836(92)90231-8 ID - Dixon1992 ER - TY - JOUR AU - Mooers, B. H. M. AU - Baase, W. A. AU - Wray, J. W. AU - Matthews, B. W. PY - 2009 DA - 2009// TI - Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme JO - Protein Sci VL - 18 UR - https://doi.org/10.1002/pro.94 DO - 10.1002/pro.94 ID - Mooers2009 ER - TY - JOUR AU - Hurley, J. H. AU - Baase, W. A. AU - Matthews, B. W. PY - 1992 DA - 1992// TI - Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme JO - J Mol Biol VL - 224 UR - https://doi.org/10.1016/0022-2836(92)90475-Y DO - 10.1016/0022-2836(92)90475-Y ID - Hurley1992 ER - TY - JOUR AU - Berman, H. M. PY - 2000 DA - 2000// TI - The protein data bank JO - Nucleic Acids res VL - 28 UR - https://doi.org/10.1093/nar/28.1.235 DO - 10.1093/nar/28.1.235 ID - Berman2000 ER -