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Table 5 Fraction of times (in percent) that a specific matrix in the PFASUM MSA Matrices set produced an MSA of at least as good (≥) quality as a specific matrix out of the Standard MSA Matrices set

From: PFASUM: a substitution matrix from Pfam structural alignments

  

PFASUM31

PFASUM43

PFASUM60

BAliBASE 3.0

BLOSUM50

67.36 (59.07)

62.69 (54.92)

62.44 (51.81)

 

BLOSUM62

71.50 (65.03)

69.43 (62.44)

67.88 (58.03)

 

PAM250

75.39 (70.21)

71.76 (63.73)

70.73 (66.84)

 

VTML160

63.47 (54.92)

61.14 (50.52)

61.66 (48.45)

 

VTML200

68.13 (57.77)

63.21 (51.81)

61.92 (50.00)

OXBench

BLOSUM50

81.52 (25.06)

83.29 (26.84)

84.30 (23.80)

 

BLOSUM62

79.24 (23.04)

81.01 (22.03)

80.76 (21.52)

 

PAM250

80.00 (32.41)

82.03 (31.65)

79.49 (33.16)

 

VTML160

79.24 (24.81)

83.80 (28.61)

82.53 (25.32)

 

VTML200

76.96 (20.76)

82.03 (22.53)

80.00 (20.51)

SABmark 1.65

BLOSUM50

67.85 (47.52)

63.36 (44.21)

65.96 (43.74)

 

BLOSUM62

63.59 (48.23)

64.30 (47.28)

64.30 (45.86)

 

PAM250

72.58 (59.57)

70.21 (56.97)

72.81 (60.05)

 

VTML160

64.78 (45.39)

60.76 (43.50)

65.25 (42.08)

 

VTML200

66.67 (47.99)

63.83 (44.21)

68.56 (44.21)

  1. The comparison for better-than-relations (>) are shown in brackets. Values are shown for all PFASUM MSA Matrices vs. Standard MSA Matrices comparisons on all three different benchmark datasets