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Table 6 Comparison of PredBLP with other methods on the independent testing dataset

From: Prediction of bioluminescent proteins by using sequence-derived features and lineage-specific scheme

Lineage Predictor Sensitivity Specificity Accuracy MCC AUC p-value
General BLProt 0.348 ± 0.022 0.903 ± 0.007 0.888 ± 0.007 0.132 ± 0.006 0.672 ± 0.010 0.002
SCMBLP 0.471 ± 0.019 0.868 ± 0.008 0.858 ± 0.007 0.157 ± 0.004 N/A 0.002
PredBLP-U 0.611 ± 0.013 0.921 ± 0.005 0.913 ± 0.004 0.294 ± 0.007 0.784 ± 0.007 N/A
Bacteria BLProt 0.584 ± 0.020 0.769 ± 0.011 0.788 ± 0.010 0.166 ± 0.008 0.674 ± 0.008 0.002
SCMBLP 0.569 ± 0.021 0.840 ± 0.013 0.831 ± 0.012 0.194 ± 0.005 N/A 0.002
PredBLP-U 0.606 ± 0.015 0.909 ± 0.010 0.899 ± 0.009 0.299 ± 0.013 0.773 ± 0.009 0.002
PredBLP-B 0.638 ± 0.017 0.927 ± 0.008 0.917 ± 0.007 0.352 ± 0.012 0.817 N/A
Eukaryota BLProt 0.417 ± 0.037 0.966 ± 0.010 0.960 ± 0.010 0.212 ± 0.018 0.719 ± 0.016 0.002
SCMBLP 0.667 ± 0.053 0.914 ± 0.014 0.912 ± 0.013 0.209 ± 0.009 N/A 0.002
PredBLP-U 0.642 ± 0.038 0.954 ± 0.007 0.951 ± 0.006 0.279 ± 0.011 0.765 ± 0.007 0.004
PredBLP-E 0.750 ± 0.037 0.946 ± 0.006 0.944 ± 0.005 0.301 ± 0.010 0.836 ± 0.006 N/A
Archaea BLProt 0.583 ± 0.057 0.842 ± 0.016 0.838 ± 0.015 0.120 ± 0.010 0.666 ± 0.007 0.002
SCMBLP 0.550 ± 0.061 0.883 ± 0.013 0.878 ± 0.012 0.154 ± 0.019 N/A 0.002
PredBLP-U 0.775 ± 0.050 0.893 ± 0.014 0.891 ± 0.013 0.244 ± 0.012 0.751 ± 0.010 0.002
PredBLP-A 0.750 ± 0.056 0.922 ± 0.012 0.920 ± 0.011 0.279 ± 0.012 0.789 ± 0.010 N/A