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Table 6 Comparison of PredBLP with other methods on the independent testing dataset

From: Prediction of bioluminescent proteins by using sequence-derived features and lineage-specific scheme

Lineage

Predictor

Sensitivity

Specificity

Accuracy

MCC

AUC

p-value

General

BLProt

0.348 ± 0.022

0.903 ± 0.007

0.888 ± 0.007

0.132 ± 0.006

0.672 ± 0.010

0.002

SCMBLP

0.471 ± 0.019

0.868 ± 0.008

0.858 ± 0.007

0.157 ± 0.004

N/A

0.002

PredBLP-U

0.611 ± 0.013

0.921 ± 0.005

0.913 ± 0.004

0.294 ± 0.007

0.784 ± 0.007

N/A

Bacteria

BLProt

0.584 ± 0.020

0.769 ± 0.011

0.788 ± 0.010

0.166 ± 0.008

0.674 ± 0.008

0.002

SCMBLP

0.569 ± 0.021

0.840 ± 0.013

0.831 ± 0.012

0.194 ± 0.005

N/A

0.002

PredBLP-U

0.606 ± 0.015

0.909 ± 0.010

0.899 ± 0.009

0.299 ± 0.013

0.773 ± 0.009

0.002

PredBLP-B

0.638 ± 0.017

0.927 ± 0.008

0.917 ± 0.007

0.352 ± 0.012

0.817

N/A

Eukaryota

BLProt

0.417 ± 0.037

0.966 ± 0.010

0.960 ± 0.010

0.212 ± 0.018

0.719 ± 0.016

0.002

SCMBLP

0.667 ± 0.053

0.914 ± 0.014

0.912 ± 0.013

0.209 ± 0.009

N/A

0.002

PredBLP-U

0.642 ± 0.038

0.954 ± 0.007

0.951 ± 0.006

0.279 ± 0.011

0.765 ± 0.007

0.004

PredBLP-E

0.750 ± 0.037

0.946 ± 0.006

0.944 ± 0.005

0.301 ± 0.010

0.836 ± 0.006

N/A

Archaea

BLProt

0.583 ± 0.057

0.842 ± 0.016

0.838 ± 0.015

0.120 ± 0.010

0.666 ± 0.007

0.002

SCMBLP

0.550 ± 0.061

0.883 ± 0.013

0.878 ± 0.012

0.154 ± 0.019

N/A

0.002

PredBLP-U

0.775 ± 0.050

0.893 ± 0.014

0.891 ± 0.013

0.244 ± 0.012

0.751 ± 0.010

0.002

PredBLP-A

0.750 ± 0.056

0.922 ± 0.012

0.920 ± 0.011

0.279 ± 0.012

0.789 ± 0.010

N/A