Fig. 1From: Biologically constrained optimization based cell membrane segmentation in C. elegans embryosComparison of typical and BCOMS approaches. Schematic comparison of membrane segmentation processes in typical (a) and BCOMS (b) approaches. a Typical approaches iterate segmentation of an input image with a parameter set, evaluation of the segmentation result, and adjustment of the parameter set until the segmentation is sufficiently accurate. b In BCOMS approach, segmentations are computed with all parameter sets and the optimal segmentation is selected by an evaluation function. The icons indicate the processed images and segmentation results, which are 3D time-lapse dataBack to article page