Fig. 2From: Biologically constrained optimization based cell membrane segmentation in C. elegans embryosSchematic of the BCOMS framework. Schematic representation of embryonic region segmentation (a) and cell membrane segmentation (b) processes. In the two-step segmentation process of the cell membrane, the optimal segmentations are selected by solving optimization problems under defined constraints. The icons indicate the processed images and segmentation results, which are 3D time-lapse data. Names and variables of the icons (for example, I, S emb ( y ) and S memb ( z )) are defined in the main textBack to article page