Table 2 Replicate estimates: Number of replicates per treatment needed to achieve maximum acceptable averages of α and β of 0.00001, 0.0001, 0.001, 0.01, 0.05, 0.1, and 0.125, at critical effects sizes of 1, 2, and 4 SD, for an independent two-tailed, two sample t-test
From: Optimal alpha reduces error rates in gene expression studies: a meta-analysis approach
Maximum acceptable average of α and β | Number of samples required | ||
|---|---|---|---|
CES = 1SD | CES = 2SD | CES = 4SD | |
0.00001 | 156 | 43 | 15 |
0.0001 | 120 | 33 | 12 |
0.001 | 85 | 24 | 9 |
0.01 | 50 | 14 | 5 |
0.05 | 27 | 8 | 3 |
0.1 | 18 | 6 | 3 |
0.125 | 16 | 5 | 3 |