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Table 1 Empirical sizes of the proposed variant-component based tests

From: Integrated genomic analysis of biological gene sets with applications in lung cancer prognosis

 

Davies

Perturbation

iTEGS-M

0.043

0.041

iTEGS-MG

0.048

0.048

iTEGS-MGC

0.045

0.045

iNOTE-chi

-

0.085

iNOTE-uni

-

0.046

  1. Type I error was calculated for a gene set of size 50 using 5000 simulations and significance threshold of α=0.05