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Table 2 Number of simulated differences (Truth) and differences obtained by NucDiff, dnadiff and QUAST

From: NucDiff: in-depth characterization and annotation of differences between two sets of DNA sequences

Group

Truth

NucDiff

dnadiff

QUAST

nonTandem

3448

6717

7460

2814

Tandem

119

116

116

0

Substitutions

164

423

234

354

Relocations

2854

2802

2211

185

Translocations

163

137

137

117

Inversions

1068

1060

1060

1053

UnalignedSeq

13

21

16

21

  1. In the nonTandem group, the values shown for the simulated differences (Truth) and QUAST are the number of events, while in the other columns the values are the sum of the number of bases involved in the differences for short and medium local differences (found by the show-snps program) and the number of events of long local differences (those causing alignment fragmentation). In the Inversions group, the numbers of simulated inversions and inversions found by NucDiff were multiplied by two to enable a fair comparison, because QUAST and dnadiff report the number of fragment ends, while NucDiff reports the number of fragments. In the Substitutions group, the values shown are the number of bases, while in the other rows the values are the number of events. The reshuffling differences are contained in the nonTandem group for QUAST, but placed in the Relocations group in all other cases