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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection

Fig. 3

A genomic locus (chr1:2,603,277-2,603,489) composed of seven CpGs. The distribution of five epialleles – inferred using the Bayesian model – are plotted for seven tumour regions (R1 to R7) and one normal sample (N). In a the tumour samples have not been corrected for normal tissue contamination whereas in b they have been. The tumour samples are shifting towards an unmethylated profile in comparison to the normal tissue. The locus lies in a large intronic region in the gene TTC34

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