Fig. 3From: Quantification of tumour evolution and heterogeneity via Bayesian epiallele detectionA genomic locus (chr1:2,603,277-2,603,489) composed of seven CpGs. The distribution of five epialleles – inferred using the Bayesian model – are plotted for seven tumour regions (R1 to R7) and one normal sample (N). In a the tumour samples have not been corrected for normal tissue contamination whereas in b they have been. The tumour samples are shifting towards an unmethylated profile in comparison to the normal tissue. The locus lies in a large intronic region in the gene TTC34Back to article page