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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Correcting nucleotide-specific biases in high-throughput sequencing data

Fig. 2

Principal component (PC) analysis of 5-mer frequencies shows clear distinctions between DNase-seq, ChIP-seq, FAIRE-seq, and ATAC-seq (a). Secondarily, clustering is evident by the lab which ran the experiment (b) (ENCODE production groups, see http://genome.uwencode.org/ENCODE/contributors.html; HAIB: HudsonAlpha, DUKE: Duke University, SYDH: Stanford/Yale/UCDavis/Harvard, UTA: University of Texas Austin, STANFORD: Stanford University, UW: University of Washington Seattle, UNC: University of North Carolina Chapel Hill). No clustering is observed by cell type (c) or by transcription factor (in ChIP-seq experiments) (d)

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