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Table 1 Average nucleotide variance before and after correction

From: Correcting nucleotide-specific biases in high-throughput sequencing data

  DNase-seq FAIRE-seq ChIP-seq ATAC-seq
Raw data 0.022 0.006 0.005 0.023
Bias corrected 0.009 0.005 0.003 0.008
  1. Variance before correction is especially high in DNase-seq and ATAC-seq as a result of DNase I and Tn5 binding preference, respectively