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Table 2 Median values, [interquartile ranges (sample size)] and Mann-Whitney U test p-values (uncorrected and Bonferroni corrected (BF)) to test for association between 14 self-reported conditions and the number heteroplasmic variants (HF > 0.3) present in the Wellderly cohort

From: SG-ADVISER mtDNA: a web server for mitochondrial DNA annotation with data from 200 samples of a healthy aging cohort

  Yes No Mann-Whitney U test Mann-Whitney U test
Condition Median [IQR (n)] Median [IQR (n)] p-value p-value (BF)
Blad_control 7.0 [5–8 (6)] 7.0 [5–10 (192)] 0.5974 1.0000
Bph 7.0 [3–9 (24)] 7.0 [5–9 (174)] 0.7815 1.0000
Copd_asthma 6.0 [3–9 (7)] 7.0 [5–9 (193)] 0.4505 1.0000
Depr_anx 7.0 [3–9 (12)] 7.0 [5–9 (188)] 0.5750 1.0000
Dyslipidemia 8.0 [6–12 (46)] 7.0 [4–9 (154)] 0.0833 1.0000
Gerd 7.0 [6–9 (19)] 7.0 [5–9 (181)] 0.4879 1.0000
Glaucoma 7.0 [4–11 (30)] 7.0 [5–9 (170)] 0.8320 1.0000
Hrt 8.5 [7–10 (12)] 7.0 [5–9 (188)] 0.0682 0.9549
Hyperten 7.5 [5–10 (80)] 7.0 [4–9 (120)] 0.0399 0.5585
Hypothyroid 7.0 [5–10 (39)] 7.0 [5–9 (161)] 0.7091 1.0000
Macular_degen 7.0 [5–9 (15)] 7.0 [5–9 (185)] 0.9132 1.0000
Osteoarth 7.0 [5–10 (87)] 7.0 [5–9 (113)] 0.3987 1.0000
Smoking_hist 7.0 [4–9 (89)] 7.0 [5–10 (111)] 0.1922 1.0000
Take_meds 7.0 [5–9 (161)] 7.0 [5–9 (39)] 0.7356 1.0000
  1. Labels: Blad_control: Bladder control problems; Bph: Benign prostatic hyperplasia; Depr_anx: Depression or anxiety; Gerd: Gastroesophageal reflux disease; Hrt: Hormone replacement therapy, Hyperten: Hypertension; Macular_degen: Macular degeneration; Osteoarth: Osteoarthritis; Smoking_hist: Smoking history; Take_meds: Currently taking medications