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Table 1 Prevalence of patients, mutations and domain-specific mutations in different cancer types

From: Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains

Cancer type Abbrevation patients Somatic Mutations Mutations on Protein Coding Regions Mutations on Pfam Domains Mutations on CATH Domains
Adrenocortical carcinoma ACC 451 22,679 21,355 8335 1090
Bladder Urothelial Carcinoma BLCA 169 169,165 154,893 69,727 11,081
Breast invasive carcinoma BRCA 983 98,882 93,405 40,390 6512
Cholangiocarcinoma CHOL 460 8593 7030 3025 484
Colon adenocarcinoma COAD 412 125,386 123,917 55,913 8055
Esophageal carcinoma ESCA 202 79,536 67,566 29,249 4340
Glioblastoma multiforme GBM 92 20,932 20,225 9905 1692
Head and Neck squamous cell carcinoma HNSC 545 151,456 131,314 59,768 9301
Kidney Chromophobe KICH 178 8739 8023 3425 489
Kidney renal clear cell carcinoma KIRC 36 51,235 47,964 21,059 3404
Kidney renal papillary cell carcinoma KIRP 269 33,247 31,433 13,530 2074
Brain Lower Grade Glioma LGG 182 47,286 42,890 19,750 3489
Liver hepatocellular carcinoma LIHC 230 89,042 82,443 36,749 5470
Lung adenocarcinoma LUAD 275 242,542 216,730 101,616 13,522
Lung squamous cell carcinoma LUSC 171 65,306 63,981 30,542 4206
Ovarian serous cystadenocarcinoma OV 524 12,751 12,214 5824 998
Pancreatic adenocarcinoma PAAD 175 82,871 72,462 29,279 4223
Pheochromocytoma and Paraganglioma PCPG 425 8706 7629 3115 472
Prostate adenocarcinoma PRAD 116 26,862 24,094 10,954 1657
Rectum adenocarcinoma READ 254 34,260 33,885 15,774 2313
Sarcoma SARC 75 83,019 71,650 30,021 4526
Skin Cutaneous Melanoma SKCM 387 53,086 49,645 23,347 2993
Stomach adenocarcinoma STAD 144 223,884 213,642 96,340 14,143
Testicular Germ Cell Tumors TGCT 356 30,293 26,170 10,902 1518
Thyroid carcinoma THCA 123 16,807 15,383 7245 1243
Thymoma THYM 248 39,467 35,892 15,655 2379
Uterine Corpus Endometrial Carcinoma UCEC 66 212,745 204,826 93,937 13,959
Uterine Carcinosarcoma UCS 57 14,212 11,803 5266 876
Uveal Melanoma UVM 80 4988 4411 2087 313
pan-cancer 7685 2,057,977 2E + 06 852,729 126,822