Skip to main content

Table 11 The result of interactome analysis for CATH candidate domains in different cancer types

From: Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains

Proteins with at least one CATH candidate domain
Cancer type #Nods #Edges Expected number of edges PPI enrichment p-value Significant or not
BRCA 315 1136 261 0 YES
COAD 377 1325 363 0 YES
GBM 28 61 9 0 YES
KIRC 49 37 13 1.62E-08 YES
KIRP 110 199 57 0 YES
LGG 21 26 4 2.55E-13 YES
LUAD 588 2173 652 0 YES
OV 6 3 0 0.000256 YES
UCEC 449 2159 671 0 YES
ACC 15 1 0 0.152 YES
BLCA 648 3067 1487 0 YES
CHOL 39 21 6 4.84E-06 YES
ESCA 191 703 180 0 YES
HNSC 370 1322 366 0 YES
KICH 18 15 2 7.81E-10 YES
LIHC 307 1065 292 0 YES
LUSC 154 177 40 0 YES
PAAD 249 610 231 0 YES
PCPG 56 35 10 5.99E-10 YES
PRAD 113 249 72 0 YES
READ 116 285 68 0 YES
SARC 285 902 223 0 YES
SKCM 281 498 145 0 YES
STAD 575 2181 762 0 YES
TGCT 78 91 9 0 YES
THCA 91 248 136 0 YES
THYM 146 411 83 0 YES
UCS 22 15 6 0.00156 YES
UVM 13 3 1 0.186 NO
Pan-cancer 457 1821 610 0 YES