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Table 6 Pfam candidate domains for Breast Invasive Carcinoma and Ovarian Serous Cystadenocarcinoma

From: Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains

Cancer Type (Percentage) Pfam Domains (Percentage)
BRCA (78.5) 7tm_4 (41.51), ATP-synt_A (0.81), Atrophin-1 (2.85), CBF_beta (2.24), COX1 (2.03), COX3 (1.12), Cadherin (23.91), Cytochrom_B_N_2 (1.12), DUF4647 (1.32), FAM219A (0.51), FRG1 (1.32), GATA (3.97), G_path_suppress (1.12), H-K_ATPase_N (0.31), Histone (7.32), NADH5_C (0.92), NADHdh (1.63), Oxidored_q4 (0.71), Oxidored_q5_N (0.81), P53 (28.48), P53_tetramer (2.03), PI3K_C2 (2.54), PI3K_P85_iSH2 (2.34), PI3K_p85B (1.02), PI3Ka (13.22), PTEN_C2 (2.03), Proton_antipo_M (3.56), Runt (2.44), T-box (4.17), TMEM247 (1.12), Tis11B_N (1.02)
OV (88.3) 7tm_4 (49.57), DUF2462 (0.43), DUF4552 (1.30), MRP-S32 (0.87), NtCtMGAM_N (2.17), ODAM (1.30), P53 (72.61), P53_tetramer (4.78), PTCRA (0.87), Sam68-YY (1.30), UPF0054 (0.87)