Table 2 Mutations (nsSNPs) in the p53 (PDBid 1TSR) core domain that were experimentally characterized
From: Vermont: a multi-perspective visual interactive platform for mutational analysis
Mutant categories | Mutations |
|---|---|
No structural effects | Arg273His |
Weakly/locally destabilising | Gly245Ser |
| Â | Arg249Ser |
| Â | Arg248Ala |
Highly destabilising/global unfolding | Cys242Ser |
| Â | His168Arg |
| Â | Val143Ala |
| Â | Ile195Thr |