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Table 10 The genes amongst the top 20 that are known to be cancer genes and their roles in the various processes required for cellular function

From: Using machine learning algorithms to identify genes essential for cell survival

Functional Class AKT1 TP53 CDH1 CCND1 BCL2 CDKN1A MYC EGFR JUN
Cell cycle X X   X X X X X  
Cell motility and interactions    X      X  
Cell response to stimuli X X   X X X    
Cellular metabolism X X   X   X X X X
Cellular processes X X X X X    X X
Development X X   X X X   X X
DNA/RNA metabolism and transcription   X      X   X
Immune system response X     X X    
Multicellular activities X     X     
Regulation of intracellular processes and metabolism X X X X X X X X X
Regulation of transcription X X      X   X
Signal transduction X X   X X X   X  
  1. X: genes involved in that particular functional process of the cell