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Fig. 3 | BMC Bioinformatics

Fig. 3

From: XBSeq2: a fast and accurate quantification of differential expression and differential polyadenylation

Fig. 3

Statistical power of different methods under various levels of background noise. Bar chart of statistical power for DESeq2, edgeR, XBSeq, XBSeq2 under low, intermediate or high level of background noise (a); Bar chart of statistical power for different methods but only with highly expressed genes (genes above 75% quantile of expression intensity) (b); Bar chart of statistical power for different methods but only with genes expressed at low levels (genes below 25% quantile of expression intensity) (c); Simulations were carried out 100 times and average statistical power were used. Dataset with 3 number of replicates per condition, 10% DEGs with 1.5-fold change was used

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