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Fig. 1 | BMC Bioinformatics

Fig. 1

From: QNB: differential RNA methylation analysis for count-based small-sample sequencing data with a quad-negative binomial model

Fig. 1

Illustration of MeRIP-Seq Protocol. In MeRIP-Seq, two types of samples (IP and input control samples) are generated. In the beginning of the protocol, RNA molecules are firstly sheared into fragments of around 100 nt. Through anti-m6A antibody, the IP sample provides unbiased measurement of the methylated RNA fragments; the input control sample reflects the basal RNA abundance

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