Fig. 6From: A sensitive short read homology search tool for paired-end read sequencing dataROC curves of profile-based short read homology search for Arabidopsis RNA-Seq data. We compared HMMER and Short-Pair on case 2, where both ends are aligned by HMMER with default E-value. Note that HMMER with GA cutoff has one data point. Using posterior probability helps remove false aligned domains and thus leads to better tradeoff between sensitivity and FP rateBack to article page