Skip to main content

Table 4 Most relevant bacterial species for classification of IBD gut microbiota versus healthy gut microbiota samples

From: Interpretation of microbiota-based diagnostics by explaining individual classifier decisions

Species name

IS-pro peak(s)

Ranked top 15 by

Alistipes finegoldii

230/395/396/400/407

all

Alistipes putredinis

235/236

all

Odoribacter splanchnicus

307/308

all

unclassified Firmicute

396

all

Escherichia coli

735/821/827/828

all

unclassified Bacteroidete

251

svm, rf, nsc

Lachnospiraceae sp.

491/605

svm, rf, lr

Bacteroides vulgatus

479

svm, nsc

Lactobacillus sp.

478

svm, lr

Streptococcus sp.

318

svm, lr

Bacteroides sp.

474

svm, lr

Streptococcus sp.

321

nsc, lr

Prevotella sp.

438

rf, nsc

Bacteroides fragilis

537

rf, nsc

Clostridium perfringens

233/235

rf, nsc

Lactobacillus sp.

244

rf, nsc

unclassified Firmicute

156

rf

  1. Ranking is based on absolute mean relevance values across all samples per classifier. Species are ordered according to the number of classifiers by which they were top-ranked. All - all classifiers; svm - linear SVM; rf - Random Forest; nsc - Nearest Shrunken Centroids; lr - L2-regularized Logistic Regression