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Fig. 5 | BMC Bioinformatics

Fig. 5

From: A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE)

Fig. 5

Predicted interactions are enriched for biologically significant attributes, and the degree of enrichment reflects interaction score. a. Fraction of interacting proteins with at least one shared GO-slim term as a function of interaction score and ontological domain. Triangle: biological process. Square: cellular component. Circle: molecular function. b. Tissue proteome abundance [23] correlation (Pearson correlation coefficient) as a function of interaction score. c. Interacting proteins in the apoptosis dataset are enriched for shared GO-slim terms relative to non-interacting protein pairs at diverse GO term breadths. d. Distribution of tissue proteome abundance correlations (Pearson correlation coefficients) for interacting and non-interacting protein pairs in D1

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