Table 1 The number of identified nodes and the number of annotated nodes are summarized for different network querying algorithms and different query/target network pairs

Human/mouse

Human/yeast

Annotated

Identified

% Annotated

Annotated

Identified

% Annotated

NatalieQ

1233

2454

0.502

1382

1753

0.788

Corbi

1357

2493

0.544

1305

1693

0.771

HubAlign

1343

2544

0.528

1692

2461

0.688

RESQUE-C

2019

4530

0.446

2735

3773

0.725

RESQUE-M

1395

2553

0.546

1669

2317

0.720

SEQUOIA

1799

3767

0.478

2807

3842

0.731

CUFID-query

1548

2946

0.525

2234

2969

0.752

Mouse/human

Mouse/yeast

Annotated

Identified

% Annotated

Annotated

Identified

% Annotated

NatalieQ

223

366

0.609

161

193

0.834

Corbi

229

355

0.645

157

193

0.813

HubAlign

245

372

0.659

206

329

0.626

RESQUE-C

383

712

0.538

368

499

0.737

RESQUE-M

246

372

0.661

227

290

0.783

SEQUOIA

296

542

0.546

336

491

0.684

CUFID-query

277

447

0.620

274

397

0.690

Yeast/human

Yeast/mouse

Annotated

Identified

% Annotated

Annotated

Identified

% Annotated

NatalieQ

767

1250

0.614

394

1223

0.322

Corbi

790

1230

0.642

424

1246

0.340

HubAlign

1003

1654

0.606

571

1683

0.339

RESQUE-C

1265

2490

0.508

772

2488

0.310

RESQUE-M

881

1574

0.560

543

1571

0.346

SEQUOIA

1171

2234

0.524

704

2337

0.301

CUFID-query

942

1507

0.625

531

1541

0.345

Overall

Annotated

Identified

% Annotated

NatalieQ

4160

7239

0.575

Corbi

4262

7210

0.591

HubAlign

5060

9043

0.560

RESQUE-C

7542

14,492

0.520

RESQUE-M

4961

8677

0.572

SEQUOIA

7113

13,213

0.538

CUFID-query

5806

9807

0.592