Table 1 Isomap cluster analysis for Calmodulin, AdK and GroEL. The data is visualized in Fig. 3

Cluster No.

Size

RMSD (1CTR)

RMSD (1CLL)

1

10

14.71±0.2

1.95±0.2

2

5

13.89±0.1

2.69±0.1

3

22

13.43±0.5

3.82±0.7

4

19

10.23±1.0

6.88±0.9

5

5

7.97±0.3

8.43±0.3

6

47

3.86±1.9

11.99±1.7

Cluster No.

Size

RMSD (1AKE)

RMSD (4AKE)

1

15

6.49±0.2

1.99±0.2

2

19

6.04±0.2

2.85±0.3

3

6

4.96±0.3

3.73±0.1

4

8

4.65±0.5

3.84±0.2

5

10

3.56±0.2

4.42±0.2

6

33

2.91±0.6

5.91±0.6

Cluster No.

Size

RMSD (1SX4)

RMSD (1SS8)

1

11

11.56±0.2

2.50±0.6

2

13

11.22±0.2

3.95±0.5

3

20

10.40±0.5

5.25±0.5

4

8

8.34±0.5

6.58±0.4

5

29

5.46±1.2

8.85±0.7

6

17

2.39±0.9

11.35±0.6