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Table 1 Clonotypes identified with HashClone analysis and IMGT validation

From: HashClone: a new tool to quantify the minimal residual disease in B-cell lymphoma from deep sequencing data

  Phase A Phase B
Study Patient Clonotype Clonotype with Clonotype with
  (only diagnosis samples) identified frequency >100 VDJ homology >80%
Pilot 1 A 1616 12 7
  B 1703 59 33
  C 2149 72 44
  D 870 10 5
  E 1398 35 21
  Average value 1547 38 22
Pilot 2 A 96 18 6
  B 278 72 11
  E 77 5 0
  Average value 150 32 6
  1. For each patient of both Pilot studies the total number of identified clonotypes (third column) is reported. The number of clonotypes with a frequency greater than 100 were selected and passed the Phase A are reported in fourth column. Then from the Phase A, clonotypes with a VDJ homology greater than 80% were selected and passed the Phase B (fifth column). The average value are reported in bold