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Table 1 MiRNAs present in the top-100 ranked candidate miRNAs that are known to be associated with diseases, as reported in the HMDD database. P-value is the result of the hypergeometric enrichment test

From: Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs

MIM ID Disease Overlap Total in HMDD p-value Known disease miRNAs
150699 leiomyoma 2 3 0.012 hsa-miR-106b, hsa-miR-93
109800 bladder cancer 6 27 0.006 hsa-miR-17, hsa-miR-182, hsa-miR-200b, hsa-miR-200c, hsa-miR-20a, hsa-miR-27a
143100 huntington disease 1 7 0.376 hsa-miR-200c
601665 obesity 2 7 0.091 hsa-miR-17, hsa-miR-30e
145500 hypertension 3 15 0.069 hsa-let-7e, hsa-miR-17, hsa-miR-20a
600634 pituitary adenoma 1 14 0.065 hsa-miR-107
133239 esophageal cancer 8 51 0.017 hsa-let-7a, hsa-let-7b, hsa-let-7c, hsa-miR-19a, hsa-miR-200c, hsa-miR-203, hsa-miR-29c, hsa-miR-98
181500 schizophrenia 17 29 2.19×10−13 hsa-miR-106b, hsa-miR-137, hsa-miR-15a, hsa-miR-15b, hsa-miR-17, hsa-miR-181b, hsa-miR-195, hsa-miR-20b, hsa-miR-26b, hsa-miR-29a, hsa-miR-29b, hsa-miR-29c, hsa-miR-30a, hsa-miR-30b, hsa-miR-30d, hsa-miR-30e, hsa-miR-9
603956 cervical cancer 2 3 0.023 hsa-miR-20a, hsa-miR-424
155601 melanoma 34 130 8.97×10−14 hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f, hsa-let-7 g, hsa-let-7i, hsa-miR-106a, hsa-miR-106b, hsa-miR-137, hsa-miR-15a, hsa-miR-15b, hsa-miR-16, hsa-miR-17, hsa-miR-181a, hsa-miR-182, hsa-miR-195, hsa-miR-196a, hsa-miR-19a, hsa-miR-19b, hsa-miR-200b, hsa-miR-200c, hsa-miR-20a, hsa-miR-20b, hsa-miR-218, hsa-miR-23b, hsa-miR-27b, hsa-miR-30a, hsa-miR-30b, hsa-miR-30d, hsa-miR-30e, hsa-miR-429, hsa-miR-506, hsa-miR-9, hsa-miR-93
151400 leukemia 6 26 0.009 hsa-miR-17, hsa-miR-181a, hsa-miR-19a, hsa-miR-19b, hsa-miR-20a, hsa-miR-27a
268210 rhabdomyosarcoma 2 7 0.112 hsa-miR-106a, hsa-miR-29a
104300 alzheimer disease 10 16 9.36×10−8 hsa-miR-106b, hsa-miR-124, hsa-miR-125b, hsa-miR-128, hsa-miR-137, hsa-miR-17, hsa-miR-181c, hsa-miR-195, hsa-miR-20a, hsa-miR-9
256700 neuroblastoma 10 29 1.23×10−5 hsa-miR-106b, hsa-miR-124, hsa-miR-128, hsa-miR-19a, hsa-miR-19b, hsa-miR-20a, hsa-miR-27b, hsa-miR-340, hsa-miR-9, hsa-miR-93
113970 burkitt lymphoma 5 10 2.05×10−4 hsa-miR-17, hsa-miR-19a, hsa-miR-19b, hsa-miR-20a, hsa-miR-93
114500 colorectal cancer 26 120 3.04×10−8 hsa-let-7b, hsa-let-7c, hsa-let-7e, hsa-miR-106a, hsa-miR-137, hsa-miR-17, hsa-miR-181a, hsa-miR-181b, hsa-miR-182, hsa-miR-195, hsa-miR-19a, hsa-miR-19b, hsa-miR-200b, hsa-miR-200c, hsa-miR-20a, hsa-miR-218, hsa-miR-23a, hsa-miR-26a, hsa-miR-26b, hsa-miR-27b, hsa-miR-29a, hsa-miR-340, hsa-miR-497, hsa-miR-9, hsa-miR-93, hsa-miR-96
260350 pancreatic cancer 23 89 6.42×10−9 hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f, hsa-let-7 g, hsa-let-7i, hsa-miR-106a, hsa-miR-128, hsa-miR-15a, hsa-miR-15b, hsa-miR-17, hsa-miR-181b, hsa-miR-182, hsa-miR-200a, hsa-miR-200c, hsa-miR-20a, hsa-miR-23a, hsa-miR-26a, hsa-miR-27a, hsa-miR-30c, hsa-miR-429, hsa-miR-96
211980 lung cancer 26 96 5.79×10−9 hsa-let-7i, hsa-miR-106a, hsa-miR-181a, hsa-miR-181b, hsa-miR-181c, hsa-miR-182, hsa-miR-19b, hsa-miR-200b, hsa-miR-200c, hsa-miR-206, hsa-miR-23a, hsa-miR-25, hsa-miR-27b, hsa-miR-301a, hsa-miR-30a, hsa-miR-30b, hsa-miR-30c, hsa-miR-30d, hsa-miR-30e, hsa-miR-32, hsa-miR-497, hsa-miR-9, hsa-miR-92a, hsa-miR-93, hsa-miR-96, hsa-miR-98
168600 parkinson disease 7 24 9.43×10−4 hsa-miR-19b, hsa-miR-29a, hsa-miR-29b, hsa-miR-29c, hsa-miR-30a, hsa-miR-30b, hsa-miR-30c
114480 breast cancer 41 170 1.96×10−13 hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f, hsa-let-7 g, hsa-let-7i, hsa-miR-1, hsa-miR-106b, hsa-miR-137, hsa-miR-15a, hsa-miR-16, hsa-miR-181a, hsa-miR-181b, hsa-miR-182, hsa-miR-195, hsa-miR-19a, hsa-miR-19b, hsa-miR-202, hsa-miR-20b, hsa-miR-23a, hsa-miR-23b, hsa-miR-27b, hsa-miR-29a, hsa-miR-29b, hsa-miR-29c, hsa-miR-302a, hsa-miR-302b, hsa-miR-302c, hsa-miR-302d, hsa-miR-30a, hsa-miR-30b, hsa-miR-30c, hsa-miR-30d, hsa-miR-340, hsa-miR-497, hsa-miR-519d, hsa-miR-520b, hsa-miR-9, hsa-miR-93, hsa-miR-96
236000 lymphoma 14 47 5.64×10−7 hsa-miR-124, hsa-miR-133b, hsa-miR-15a, hsa-miR-17, hsa-miR-181a, hsa-miR-19a, hsa-miR-19b, hsa-miR-200b, hsa-miR-200c, hsa-miR-20a, hsa-miR-20b, hsa-miR-218, hsa-miR-26a, hsa-miR-29c
155255 medulloblastoma 9 57 0.013 hsa-miR-106a, hsa-miR-17, hsa-miR-181b, hsa-miR-182, hsa-miR-19a, hsa-miR-19b, hsa-miR-20a, hsa-miR-30a, hsa-miR-96
137215 gastric cancer 27 123 3.56×10−9 hsa-let-7f, hsa-let-7 g, hsa-miR-106a, hsa-miR-107, hsa-miR-124, hsa-miR-130a, hsa-miR-17, hsa-miR-181a, hsa-miR-181b, hsa-miR-182, hsa-miR-195, hsa-miR-200b, hsa-miR-200c, hsa-miR-20a, hsa-miR-27a, hsa-miR-27b, hsa-miR-29a, hsa-miR-30b, hsa-miR-30c, hsa-miR-340, hsa-miR-372, hsa-miR-373, hsa-miR-429, hsa-miR-497, hsa-miR-503, hsa-miR-519a, hsa-miR-9