Fig. 2From: Reconstructing cancer karyotypes from short read data: the half empty and half full glassThe paired ends read alignment signature of a deletion rearrangements. The grey area on the reference genome between points A and B was deleted in the sample genome. Any read whose gap falls between A and B on the sample genome will have its ends aligned to locations that are far apart on the same chromosome, indicating a deletion. Other rearrangements leave unique signatures in a similar mannerBack to article page