Fig. 5
From: Software for rapid time dependent ChIP-sequencing analysis (TDCA)
TC XR-seq analysis in NHF1 cells. a 271 hills from chromosomes 21 and 22 ordered by the difference of their TTIfall and TTIrise. This difference (TTIfall - TTIrise) reflects the clearance rate of DNA excised from these loci. b Scatter plot of the signal increase (incline) TTI (TTIrise) and signal decrease (decline) TTI (TTIfall) of 271 hills from chromosomes 21 and 22. Two clusters are apparent from this analysis that indicating either slow (top right quadrant) or fast (bottom left quadrant) excision of DNA at loci. c TDCA modeling of the locus at chromosome 21:9,499,501–9,500,001. Individual coverage values are shown as black dots and can be visually seen in the sequencing tracks shown to the right. d As in (c) except for the locus at chromosome 22:40,153,001–40,153,501