Fig. 12

Collective protein carbon alpha motions projected over PC1, PC2, and PC3 simultaneously. The projection of time window 14 ns–24 ns, with DET value larger than the upper 95% confidence level, simultaneously along the principal component eigenvectors with the three largest eigenvalues. Regions a, b, c, d, and e show clear collective loop domain motions. The figure is prepared using VMD [65]