BMC Bioinformatics

Table 5 Testing larger sketch sizes for MHAP. Starting with the value we have used for testing, 1256, the sketch size is increased with increments of 512 up to 3816

From: HISEA: HIerarchical SEed Aligner for PacBio data

Genome	Parameter	MHAP skecth size
		1256	1768	2280	2792	3304	3816
E.coli	Sensitivity	83.74	85.75	86.52	86.87	87.05	87.16
	Specificity	99.90	99.86	99.84	99.82	99.81	99.80
	Precision	97.15	96.99	96.82	96.89	96.88	97.70
	F1-score	89.95	91.02	91.38	91.61	91.70	92.13
S.cerevisiae	Sensitivity	62.08	63.67	64.32	64.52	64.62	64.69
	Specificity	99.77	99.72	99.66	99.63	99.58	99.56
	Precision	89.29	88.79	88.69	88.62	88.55	88.30
	F1-score	73.24	74.16	74.56	74.67	74.72	74.67
C.elegans	Sensitivity	80.43	81.81	82.37	82.62	82.69	82.73
	Specificity	99.97	99.93	99.90	99.88	99.85	99.82
	Precision	45.46	35.71	29.32	25.80	23.75	22.13
	F1-score	58.09	49.72	43.25	39.32	36.90	34.92
A.thaliana	Sensitivity	76.19	77.05	77.38	77.49	77.55	77.57
	Specificity	99.91	99.87	99.86	99.85	99.84	99.83
	Precision	88.78	88.50	88.68	88.35	88.55	88.33
	F1-score	82.00	82.38	82.65	82.56	82.69	82.60
D.melanogaster	Sensitivity	71.86	73.36	73.89	74.12	74.24	74.30
	Specificity	99.94	99.92	99.91	99.88	99.87	99.86
	Precision	72.47	72.00	72.07	72.46	71.45	71.62
	F1-score	72.16	72.67	72.97	73.28	72.82	72.94

Note that the results for the first column (sketch size 1256) appear also in Table 2. They are repeated here for comparison convenience

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