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Table 6 Testing higher number of minimizers for Minimap. Starting with the value we have used for testing, w=5, we increase the number of minimizers by decreasing w all the way to the smallest value w=1. Note that the results for the first column (w=5) appear also in Table 2. They are repeated here for comparison convenience

From: HISEA: HIerarchical SEed Aligner for PacBio data

Genome

Parameter

Minimap window size

  

5

4

3

2

1

E.coli

Sensitivity

91.80

93.08

94.13

95.24

96.29

 

Specificity

99.93

99.92

99.93

99.92

99.91

 

Precision

97.13

97.22

97.42

97.51

97.58

 

F1-score

94.39

95.10

95.75

96.36

96.93

S.cerevisiae

Sensitivity

9.35

9.64

9.94

10.36

11.00

 

Specificity

99.98

99.98

99.97

99.97

99.97

 

Precision

94.30

94.18

93.28

91.90

88.58

 

F1-score

17.01

17.49

17.97

18.62

19.57

C.elegans

Sensitivity

85.38

86.63

87.63

88.77

89.80

 

Specificity

99.98

99.98

99.98

99.98

99.97

 

Precision

89.80

89.77

89.05

88.11

85.76

 

F1-score

87.53

88.17

88.33

88.44

87.73

A.thaliana

Sensitivity

23.55

26.90

31.21

37.08

45.56

 

Specificity

99.97

99.98

99.96

99.96

99.96

 

Precision

84.00

84.77

85.48

86.43

87.94

 

F1-score

36.79

40.84

45.73

51.90

60.02

D.melanogaster

Sensitivity

40.72

42.82

45.51

49.11

54.00

 

Specificity

99.99

99.98

99.98

99.98

99.97

 

Precision

83.93

83.12

82.87

81.85

81.25

 

F1-score

54.84

56.52

58.75

61.39

64.88