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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Redundancy analysis allows improved detection of methylation changes in large genomic regions

Fig. 2

RDA biplot of the HER2 region (BRCA dataset) for crude and adjusted models. The adjusted model also includes surrogate variables in the analysis. The points represent the samples and are coloured according to HER2 status (HER2-, Negative; HER2+, Positive). Negative and Positive labels are placed at the centroid of their respective groups. CpGs most strongly associated with the RDA components are represented with labels. R2 is the proportion of variance in methylation data explained by the model. The p-value of the RDA model was computed by sampling the HER2 sample status variable

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