From: OVAS: an open-source variant analysis suite with inheritance modelling
Pipeline stage | Module name | Runtime (seconds) |
---|---|---|
 | Adding genes | 125 |
Annotation | Adding function | 28.7 |
 | Adding Zygosity | 0.81 |
Filtering | Physical location filter | 1.02 |
 | Read depth filter | 1.26 |
 | Call quality filter | 0.93 |
 | AAF filter | 143 |
 | Mutation type filter | 1.08 |
 | Novel variant filter | 1.12 |
 | Same gene filter | 22.5 |
 | Same variant filter | 26.1 |
 | AD inheritance | 0.83 |
Trait penetrance model | AR inheritance | 1.22 |
 | XD inheritance | 0.74 |
 | XR inheritance | 1.39 |
 | Mosaicism | 0.94 |
Extended annotation | Isoform context | 2.28 |
 | Protein context | 4.10 |
 | Gene expression | 145 |