Fig. 4

Clustering of regulatory network into 5 functional modules. Signaling pathway enrichment analysis in each functional module obtained from clustering of gene-gene interaction network. The color represents the functional module in clustered network. The blue color represents the module 0, light green represents module 1, khaki color represents module 2, bright green represents module 3 and in the last, module 4 is represented by violet color. The bar plot for each functional module shows the number of genes enriched in signaling pathways, by taking the cut-off for corrected p-value ≤ 0.05