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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Large scale analysis of protein conformational transitions from aqueous to non-aqueous media

Fig. 4

Structural representation of Ras protein conformers. a Cartoon representation of state 1 (red, PDB ID = 1x2d_B) and state 2 (blue, PDB ID = 1ctq_A) conformers (inactive and active respectively) of human Ras protein. In stick representation are Mg++ and GTP bound ligands, Thr 35 (switch I) and Tyr (switch II) essential components for Ras activity. b Cartoon representation of AA maximum RMSD pair, 1xd2_B (light purple) and 4dls_A (cyan) showing again the state 1 and state 2 respectively. c Cartoon representation of AO maximum RMSD pair, where 1p2s_A (light green) and 4nym_R (cyan) showing state 1 and state 2 respectively. d Cartoon representation of maximum RMSD OO pair showing 1p2s_A (light green) and 3rs5_A (light orange) showing both structures the state 2. 1p2s_A was resolved in 50% trifluoroethanol and 3rs5_A in 55% dimethylformamide

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