Fig. 8
From: CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses
Modular analysis of Leishmaniasis. a Gene Set Enrichment Analyses showing the module activity on each class of samples. “Healthy” = uninfected subjects; “SickBeforeTreat” = Leishmania-infected patients before treatment; “SickAfterTreat” = Leishmania-infected patients after treatment. b Over Representation Analysis of modules M7. Bar graphs shows the -log10 Adjusted P-value of the enrichment between genes in modules and gene sets from Reactome Pathway database. The vertical dashed grey line indicates an adjusted P-value of 0.01. c Gene networks of modules M3 and M9. The top ten most connected genes (hubs) are labeled and colored based on their “origin”: if originally present in the CEMiTool module, they are colored blue; if inserted from the interactions file, they are colored red. The size of the node is proportional to its degree