Fig. 5From: The VAAST Variant Prioritizer (VVP): ultrafast, easy to use whole genome variant prioritization toolVVP percentile scores for ClinVar CFTR and BRCA2 variants. Violin and box plots are described in Fig. 4. Percentile Scores are shown on the y-axis; benign variants on the left, pathogenic on the right. a CFTR. Pathogenic: 897 variants, mean score: 100. Benign: 466 variants, mean score: 17. b BRCA2. Pathogenic: 249 variants, mean score: 93. Benign: 6 variants, mean score: 34. All scores were generated without using genotype information, i.e. the variant was scored as a heterozygoteBack to article page