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Table 1 Parameters related to specific relationships for the proposed model

From: Pathway-based approach using hierarchical components of rare variants to analyze multiple phenotypes

 

Coefficients

 

Coefficients

Relationship

P k → Y

βk1, ..., β kQ

Relationship

G tk → Y

w tk βk1, ..., w tk β kQ

P k → Y q

β kq

G tk → Y q

w tk β kq

  1. P k indicates the kth pathway, Y q is the qth phenotype, Y* indicates all phenotypes, and G tk indicates the tth gene in the kth pathway