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Fig. 3 | BMC Bioinformatics

Fig. 3

From: An information-theoretic approach to the modeling and analysis of whole-genome bisulfite sequencing data

Fig. 3

Examples of methylation level PMFs within a GU containing 7 CpG sites with a high JSD value between a test and a reference sample: a The observed high JSD value of 1 is mainly driven by a high absolute dMML of 0.7. b The high JSD value of 0.9 is mainly driven by a high absolute dNME of 0.6. c A high JSD value can be due to statistical factors other than a nonzero dMML or a nonzero dNME. The depicted PMFs result in the highest JSD value of 1, despite the fact that they result in zero dMML and dNME values

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