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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis

Fig. 7

Example of normalizing the IFPs of three EGFR mutants to the same length by adding zeros. a For delE746_A750, 35 (5×7, where 7 means the 7 bits fingerprint for each residue) zeros are added between residues K745 and T751, due to the deletions of delE746_A750, 28 (4×7) zeros are added between residues A763 and Y764, due to the insertions of A763_Y764insFQEA, and 21 (3×7) zeros are added between residues V769 and D770, due to the insertions of V769_D770insASV. b For V769_D770insASV, 28 (4×7) zeros are added between residues A763 and Y764, due to the insertions of A763_Y764insFQEA. c For A763_Y764insFQEA, 21 (3×7) zeros are added between residues V769 and D770, due to the insertions of V769_D770insASV

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BMC Bioinformatics

ISSN: 1471-2105

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