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Table 1 Selected EGFR mutations and their corresponding drug sensitivity to gefitinib/erlotinib based on the survey carried out by [49]

From: Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis

 

Category

Mutations

Sensitivity

1

Del 19

delE746_A750

High

2

delL747_P753insS

3

delL747_T751

4

delL747_A750insP

5

delL747_S752

6

delE746_S752insV

7

delE746_P753insVS

8

delL747_T751insP

9

delE746_T751insA

10

delL747_P753

11

delS752_I759

12

L858R

L858R

13

E709X

E709A

Moderate

14

E709K

15

Del 18

delE709_T710insD

16

G719X

G719A

17

G719C

18

G719S

19

Ins 19

I744_K745insKIPVAI

20

S768I

S768I

21

L861Q

L861Q

22

Ins 20

A763_Y764insFQEA

23

V769_D770insASV

Low

24

D770_N771insSVD

25

H773_V774insH

26

H773_V774insPH

27

H773_V774insNPH

28

T790 M

T790 M

29

T790 M_L858R

30

T790 M_delE746_A750

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BMC Bioinformatics

ISSN: 1471-2105

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