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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Notos - a galaxy tool to analyze CpN observed expected ratios for inferring DNA methylation types

Fig. 5

CpN o/e analyzed by Notos for Neurospora crassa. The red line corresponds to the estimated density via KDE. Full vertical blue lines indicate modes with PM ≥ 0.1. Shaded blue areas around the modes correspond to bootstrap confidence intervals with a default level of 95%. The panels show kernels of transcripts for CpG o/e (a) and CpA o/e (b), and for repeats (c and d), respectively. In this case CpG and CpA o/e ratios were calculated for spliced exons and repeat regions of the N. crassa genome. Both o/e frequency distributions are clearly unimodal, but for the CpA o/e in repeats there is a shift towards 0.5 which is concordant with DNA methylation only in this context (repeats and CpA) in this species

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