Fig. 7
From: Robust volcano plot: identification of differential metabolites in the presence of outliers
Metabolomic biomarker identification for breast cancer. a Heatmap plot of up-regulation and down-regulation for the 37 differential metabolites identified by the proposed method (red indicates cancer samples and blue indicates control samples). b Clustering of the 37 differential metabolites for the experimental dataset. Hierarchical clustering was used after normalizing the experimentally measured breast cancer dataset by auto-scaling. c Ranking of the 37 differential metabolites according to the importance score calculated using an SVM classifier with radial basis kernel function